Eliprodil 是NR2B-NMDA受体高效选择性抑制剂,IC50值1uM。它对NR2A-和NR2C-NMDA受体作用较弱,可用于研究帕金森病和运动障碍治疗的试验。
半岛bd体育手机客户端 描述
Eliprodil(SL-820715), a non-competitive NR2B-NMDA receptor antagonist(IC50: 1 uM), less effective for NR2A- and NR2C-containing receptors(IC50>100 uM). It has been used in trials studying the treatment of Parkinson Disease and Movement Disorders.
Cas No.
119431-25-3
分子式
C20H23ClFNO
分子量
347.86
别名
依利罗地;SL-820715
储存和溶解度
DMSO:25 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years