NITD-2 是一种登革病毒 (DENV) 聚合酶抑制剂，可抑制 DENV RdRp 介导的 RNA 延伸。

NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in humans. Neither vaccine nor antiviral therapy is currently available for DENV.

NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration.NITD-2 inhibits de novo RNA synthesis[1].

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C23H19N3O4S

433.48

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years