半岛bd体育手机客户端 描述
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
体外活性
Corynoxine B, a natural autophagy inducer, restores the deficient cytosolic translocation of HMGB1 and autophagy in cells overexpressing SNCA [1].
体内活性
Corynoxine B exhibited prolongation of the thiopental-induced hypnosis on oral administration in mice [2].
Cas No.
17391-18-3
分子式
C22H28N2O4
分子量
384.47
别名
柯诺辛碱 B;柯诺辛碱B
储存和溶解度
DMSO:80 mg/mL (208.07 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years