DeSmopressin acetate (16679-58-6 free base) 是抗利尿激素精氨酸加压素的合成类似物。
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Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin works by limiting the amount of water that is eliminated in the urine. Desmopressin binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.
Cas No.
62288-83-9
分子式
C48H68N14O14S2
分子量
1129.28
别名
Desmopressin acetate;DDAVP;醋酸去氨加压素
储存和溶解度
Ethanol:Soluble
DMSO:10 mM
H2O:50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years