Mal-PEG1-acid是一种不可降解 (non-cleavable) 的含 1 个单元 PEG 的 ADC linker，可用于合成 抗体偶联药物 (ADC)。
| Cas No. |
760952-64-5 |
| Canonical SMILES |
O=C(O)CCOCCN1C(C=CC1=O)=O |
| 分子式 |
C9H11NO5 |
| 分子量 |
213.19 |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs) ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. [1]. Karpov AS, et al. Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody-Drug Conjugates. ACS Med Chem Lett. 2018 Jun 28;9(8):838-842. |
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