Pomalidomide 4'-alkylC8-amine 是一种合成的 E3 连接酶配体-接头偶联物,包含基于 Thalidomide 的 cereblon 配体和 PROTAC 技术中使用的接头。
Cas No. |
2446474-06-0 |
别名 |
泊马利度胺4'-烷基C8-胺 |
Canonical SMILES |
NCCCCCCCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O.Cl |
分子式 |
C21H28N4O4.HCl |
分子量 |
436.93 |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
Functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license. |