| CAS NO: | 174422-72-1 |
| 包装 | 价格(元) |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 174422-72-1 |
| 别名 | MAL-C2-环己基羧基酰肼(盐酸盐) |
| Canonical SMILES | Cl[H].O=C1C=CC(N1CC(CC2)CCC2C(NN)=O)=O |
| 分子式 | C12H18ClN3O3 |
| 分子量 | 287.74 |
| 溶解度 | DMSO: 16.67 mg/mL (57.93 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 | Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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