Iodo-PEG3-Iodide 是一种基于 PEG 的 PROTAC 接头。 Iodo-PEG3-Iodide 可用于合成 MT802 和 SJF620。 MT-802 和 SJF620 是有效的 PROTAC BTK 降解剂，DC50 分别为 1 nM 和 7.9 nM。
| Cas No. |
36839-55-1 |
| 别名 |
1,2-双(2-碘代乙氧基)乙烷 |
| 分子式 |
C6H12I2O2 |
| 分子量 |
369.97 |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
PEG3 diiodide is a homobifunctional linker with two iodide functional groups which are very reactive against many nucleophiles like thiols, amines, alkoxy anions, etc. Can be used to synthesize hydrophilic symmetrical conjugates. |
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