DBCO-C6-acid - 半岛电竞官方网址

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DBCO-C6-acid

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

半岛bd体育手机客户端介绍

DBCO-C6-acid 是一种不可降解 (non-cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs) 的合成。DBCO-C6-acid 可用于合成 carmaphycin 类似物。

Cas No.	1425485-72-8
Canonical SMILES	O=C(CCCCC(O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
分子式	C₂₁H₁₉NO₃
分子量	333.38
溶解度	DMSO : 100 mg/mL (299.96 mM)
储存条件	Store at -20℃
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References: [1]. Almaliti J, et al. Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.