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Azido-PEG8-amine
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Azido-PEG8-amine图片
CAS NO: 857891-82-8
包装: 100mg
市场价: 2070元

半岛bd体育手机客户端 介绍
Azido-PEG8-amine 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
Cas No. 857891-82-8
别名 O-(2-氨基乙基)-O′-(2-叠氮乙基)七聚乙二醇
分子式 C18H38N4O8
分子量 438.52
储存条件 4°C, protect from light
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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