Damascenone ((E/Z)-Damascenone) is an active compound of Epipremnum pinnatum with anti-inflammatory activity[1]. Damascenone is a mixture complex of E-isomer-Damascenone and Z-isomer Damascenone.

β-Damascenone also inhibits the upregulation of inflammatory proteins as demonstrated by immune assays for cell surface E-selectin and secreted TNF-α[1].β-Damascenone inhibits NF-κB signaling pathway in vitro in human cellular systems that has been activated with different inflammatory stimuli[1].

[1]. San-Po Pan, et al. C13 Megastigmane Derivatives From Epipremnum pinnatum: β-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-κB Signaling