Epertinib hydrochloride 是口服可逆的选择性EGFR、HER2和HER4抑制剂，IC50值分别为 1.48、7.15 和 2.49 nM，具有抗肿瘤活性。

Epertinib hydrochloride shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.

2071195-74-7

C30H28Cl2FN5O3

596.48

S-22611 hydrochloride

DMSO:125 mg/mL (209.56 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years