DBCO-PEG4-VA-PBD 是一种抗体偶联药物，由抗肿瘤抗生素 Pyrrolobenzodiazepine (PBD) 和 DBCO-PEG4-VA 连接而成。
| Cas No. |
2241644-09-5 |
| 分子式 |
C80H87N9O16 |
| 分子量 |
1430.6 |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
DBCO-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |
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