Isorubrofusarin-6-O-β-gentiobioside 来源于 Cassia obtusifolia Linn 种子,对 AChE 和 BACE1 具有良好的抑制活性。
半岛bd体育手机客户端 描述
Isorubrofusarin-6-O-β-gentiobioside is derived from from Cassia obtusifolia Linn seeds and shows promising inhibitory activity against AChE and BACE1.
体外活性
The SARs results emphasized the importance of gentiobiosyl moiety in Isorubrofusarin-6-O-β-gentiobioside for AChE inhibition, whereas the presence of hydroxyl group at C-8 and the glucosyl moiety at the C-6 position in the Isorubrofusarin-6-O-β-gentiobioside appeared to largely determine BACE1 inhibition[1].
Cas No.
200127-93-1
分子式
C27H32O15
分子量
596.53
储存和溶解度
DMSO:3 mg/mL (5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years