Isolinderalactone 具有抗炎和抗癌能力,具有中等的 iNOS 抑制活性,IC50 值为 0.30 uM。
半岛bd体育手机客户端 描述
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
体外活性
Isolinderalactone induces apoptosis in MDA-MB-231 cells and suppresses STAT3 signaling pathway through regulation of SOCS3 and miR-30c, may become a novel treatment for triple-negative breast cancer in the future.
Cas No.
957-66-4
分子式
C15H16O3
分子量
244.29
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years