11β-HSD1-IN-11 是一种竞争性的 11β-HSD1 抑制剂，对大鼠和人的 11β-HSD1 的 IC50 分别为 0.34 μM 和 0.13 μM。

11β-HSD1-IN-11 is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively.

A single dose of the 11β-HSD1 inhibitor Merck 544 reduced the overall abundance of 11β-HSD1-IN-11 (Compound c1a) (15 mg/kg; oral gavage; once) in the rat liver[1].

859721-81-6

C15H11F3O3S

328.31

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years