DryocRassin ABBA 是一种从苦参中提取的黄酮类天然产物,具有抗病毒和抗菌活性。它抑制树突状细胞的免疫刺激功能,延长同种异体皮肤移植成活率。
半岛bd体育手机客户端 描述
Dryocrassin ABBA is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities.
体外活性
Dryocrassin ABBA and its analogues (b5 and e2) showed better NAs inhibitory activity against Anhui H7N9 with IC values of 3.6 μM, 2.5 μM and 1.6 μM.?For the highly resistant Shanghai N9, these compounds can also show medium inhibitory activities.?Docking results indicated the direct interaction of synthesized 3 hits with the key K294 by hydrogen bonds, but no direct interaction of OSV with the key K294 was observed in Shanghai N9.?dryocrassin ABBA and its analogues especially AB, which consisted of polyphenol groups may have beneficial effects on treating avian influenza H7N9 virus[2].
Cas No.
12777-70-7
分子式
C43H48O16
分子量
820.83
别名
Dryocrassin;东北贯众素
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years