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3-Oxo-hop-22(29)-ene
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3-Oxo-hop-22(29)-ene图片
CAS NO: 25615-11-6
包装与价格：
包装 价格(元)
100mg 电议
250mg 电议
500mg 电议

半岛bd体育手机客户端 介绍
3-Oxo-hop-22(29)-ene 是一种 yeast α-glucosidase抑制剂。3-Oxo-hop-22(29)-ene 具有中等的抗克氏锥虫和抗墨西哥利什曼原虫活性。3-Oxo-hop-22(29)-ene 具有微弱的抗炎活性。
生物活性

3-Oxo-hop-22(29)-ene is ayeast α-glucosidaseinhibitor. 3-Oxo-hop-22(29)-ene shows a moderate effect on the viability ofT. cruziandL. mexicana. 3-Oxo-hop-22(29)-ene shows marginal activity of anti-inflammatory[1].
体外研究
(In Vitro)

3-Oxo-hop-22(29)-ene (compound 2) (50 μM; 24 hours) reduces the viability ofT. cruziby more than 20%, and has a moderate effecton onT. rangeliandL. mexicana[1].
3-Oxo-hop-22(29)-ene (10, 100 μM; 48 hours) causes 1.51% and 7.39% inhibition activity to yeast α-glucosidase respectively[1].

Cell Viability Assay[1]

Cell Line: Saccharomyces cerevisiae (type 1) and mammalian yeast (type 2) α-glucosidases,T. cruzi,T. rangeli,L. mexicana
Concentration: 10 μM, 50 μM, 100 μM
Incubation Time: 24 hours, 48 hours
Result: Reduced the viability ofT. cruziby more than 20%, and had a moderate effecton onT. rangeliandL. mexicana
Inhibited Yeast α-glucosidase.
体内研究
(In Vivo)

3-Oxo-hop-22(29)-ene (0.31 μmol/ear; application; once) decreases 17.50 % the inflammation of mouse ear edema model[1].

Animal Model: Adult male CD-1 mice (25-30 g) (Mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA))[1]
Dosage: 0.31 μmol/ear
Administration: Apply to both faces of the right ear; once
Result: Decreased 17.50% the inflammation of mouse ear edema model.
分子量

424.70
Formula

C30H48O
CAS 号

25615-11-6
结构分类
  • Terpenoids
  • Triterpenes
来源
  • Plants
  • Euphorbiaceae
  • Cnidoscolus spinosusLundell
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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