Fenofibric acid-d6 (FNF acid-d6) is the deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is aPPARactivitor, withEC₅₀s of 22.4 μM, 1.47 μM, and 1.06 μM forPPARα,PPARγandPPARδ, respectively; Fenofibric acid also inhibitsCOX-2enzyme activity, with anIC₅₀of 48 nM.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

324.79

C₁₇H₉D₆ClO₄

1092484-69-9

非诺贝特酸 d6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.