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CypD-IN-3
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CypD-IN-3图片
CAS NO: 2651994-75-9
包装与价格:
包装 价格(元)
100mg 电议
250mg 电议
500mg 电议

半岛bd体育手机客户端 介绍
CypD-IN-3 是一种有效的亚型选择性亲环蛋白 D (CypD) 抑制剂。CypD-IN-3 具有亲环蛋白 D (CypD) 亲和力, IC50值为 0.01 μM。CypD-IN-3 可用于多种疾病的研究,如氧化应激、神经退行性疾病、肝病、衰老、自噬和糖尿病。
生物活性

CypD-IN-3 is a potent and subtype-selectivecyclophilin D (CypD)inhibitor. CypD-IN-3 has CypD affinity with anIC50value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging,autophagyand diabetes[1].

IC50& Target

IC50: 0.01 μM (CypD); 1.1 μM (CypA); 0.21 μM (CypB); 0.31μM (CypE)[1]

体外研究
(In Vitro)

CypD-IN-3 (B52) has selectivity for inhibiting CypD, CypA, CypB and CypE with IC50values of 0.01 μM, 1.1 μM, 0.21 μM and 0.31 μM, respectively[1].
CypD-IN-3 (10 μM) inhibits mitochondrial permeability transition pore opening in isolated mitochondria[1].

分子量

972.09

Formula

C53H61N7O11

CAS 号

2651994-75-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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