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(-)-Carvone

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

6485-40-1

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

半岛bd体育手机客户端介绍

(-)-Carvone 是一种昆虫神经毒素，是一种不可逆的乙酰胆碱酯酶 ( AChE) 抑制剂。(-)-Carvone 可作为驱鸟剂，抑制幼虫生长，降低幼虫孳生率，增加幼虫死亡率。

生物活性

(-)-Carvone is an insect neurotoxin and a irreversibleacetylcholinesterase(AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae^[1]^[2].

IC₅₀& Target^[1]

eel AChE

2.19 mM (Ki)

体外研究
(In Vitro)

(-)-Carvone (3.04 mM; 30 min) inactivates eel AChE with K_ivalue of 2.19 mM^[1].

体内研究
(In Vivo)

(-)-Carvone (5% in absolute ethanol v/v, 20 μL; application to the thoraces ventral surfaces) inhibits AChE such as horse serum cholinesterase, house fly head cholinesterases, and head and thorax cholinesterases from the Madagascar roach in vitro^[1].
(-)-Carvone (0.05%-0.1% w/v; p.o.; 7 d) inhibitsE. insulanalarvae growth, decreases weight of larvae^[2].

Animal Model:	Female roaches (Gromphadorhina portentosa) (6.4 g-6.8 g)^[1]
Dosage:	5% in absolute ethanol v/v, 20 μL
Administration:	Application to the ventral surfaces of their thoraces; decapitated and crude at various time intervals (0, 2, 4, 5, 20, 24, and 26 hr)
Result:	Inhibited the activity of AChE in the extracts of both the head and thorax.