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11-deoxy Prostaglandin E1
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
11-deoxy Prostaglandin E1图片
CAS NO: 37786-00-8
包装与价格：
包装 价格(元)
500μg 电议
1mg 电议
5mg 电议
10mg 电议

半岛bd体育手机客户端 介绍
Cas No. 37786-00-8
别名 11脱氧前列腺素E1
化学名 9-oxo-15S-hydroxy-prost-13E-en-1-oic acid
Canonical SMILES O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)CC1
分子式 C20H34O4
分子量 338.5
溶解度 DMF: >100 mg/ml (from PGE1),DMSO: >50 mg/ml (from PGE1),Ethanol: >50 mg/ml (from PGE1),PBS pH 7.2: >1.6 mg/ml (from PGE1)
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述 11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1. Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2. However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat cells with an EC50 of 0.25 uM. 11-deoxy PGE1 also exhibits vasodepressor and bronchodilator responses in guinea pigs. 11-deoxy PGE1 exhibits selectively for the mouse EP3 receptor and is essentially equipotent to PGE1 at this receptor subtype. The Ki values for binding to the mouse EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively.
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