| Cas No. |
21562-57-2 |
| 别名 |
前列腺素E1醇 |
| 化学名 |
1,11α,15S-trihydroxy-prost-13E-en-9-one |
| Canonical SMILES |
O=C1[C@H](CCCCCCCO)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1 |
| 分子式 |
C20H36O4 |
| 分子量 |
340.5 |
| 溶解度 |
DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 文献引用 |
|
| 半岛bd体育手机客户端 描述 |
Prostaglandin E1 (PGE1) alcohol is a non-irritant bronchodilator, with relaxant activity on the human bronchial muscle in vitro, comparable to PGE1 at concentrations of 0.01 to 10.0 ug/ml. Asthmatics receiving single dose inhalation treatments reported significant but short-acting bronchodilation at doses of 10 and 30 ug. PGE1 alcohol binds to the mouse recombinant EP3 and EP4 receptors with Ki values of 330 and 190 nM, respectively. |
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