Cas No. |
23918-98-1 |
别名 |
4-(6-氨基-9H-嘌呤-9-基)-4-脱氧-D-赤酮酸 |
Canonical SMILES |
NC1=NC=NC2=C1N=CN2C[C@@H](O)[C@@H](O)C(O)=O |
分子式 |
C9H11N5O4 |
分子量 |
253.2 |
溶解度 |
1N HCl: slightly soluble |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase (SAAH; IC50 = 7 nM). It inhibits growth of C. parvum parasites (MIC50 = 3 μM) without exhibiting cytotoxicity in HCT-8 cells (CC50 = >1 mM). Dietary administration of D-eritadenine (50 mg/kg) increases liver microsomal phosphatidylethanolamine concentration and decreases liver microsomal δ6 desaturase activity and plasma cholesterol levels in rats. |