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LH-RH(7-10)
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
LH-RH(7-10)图片
CAS NO: 38482-71-2
包装与价格：
包装 价格(元)
100mg 电议
250mg 电议
500mg 电议

半岛bd体育手机客户端 介绍
LH-RH (7-10) 是一种四肽，性腺激素释放激素 (LHRH) 经垂体和下丘脑降解的主要降解产物之一。LH-RH (7-10) 在巨噬细胞、I 型样和 II 型肺细胞中产生。
生物活性

LH-RH (7-10) is a tetrapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (7-10) produced in macrophages, type I-like and type II pneumocytes[3].
体外研究
(In Vitro)

The formation of LHRH 4-10, LHRH 7-10, and LHRH 6-10Co-incubation are inhibited by known enzyme inhibitors includingCaptopril(HY-B0368) (an ACE inhibitor),Thiorphan(HY-W013375) (an EP24.11 inhibitor), andEthylenediaminetetraacetic acid(HY-Y0682) (an EP24.15 inhibitor)[3].
LH-RH (7-10) inhibits the binding of125I-labeled GnRH to monoclonal antibody P81662with an IC50value of 1.7 nM[4].
体内研究
(In Vivo)

LH-RH (7-10) (i.v.) increases esterase activity in plasma kinin system in rats[1].
LH-RH (7-10) (ntracarotid infusion i.v.; single dose) stimulates a significant increase in plasma LH concentration in the jugular vein[2].

Animal Model: New Zealand White Rabbit[2]
Dosage: 100, 500 and 2500 ng dissolved in 0-9% (w/v) NaCl solution and diluted
Administration: Ntracarotid infusion; infused with a constant volume of 7-5 mL per 30 min
Result: Caused LH release in the female rabbit during various reproductive conditions.
分子量

440.54
Formula

C19H36N8O4
CAS 号

38482-71-2
Sequence Shortening

LRPG-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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