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IDO inhibitor 1
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IDO inhibitor 1图片
CAS NO: 1204669-37-3
包装与价格:
包装 价格(元)
10mM (in 1mL DMSO) 电议
5mg 电议
10mg 电议
25mg 电议
50mg 电议

半岛bd体育手机客户端 介绍
Indoleamine-2,3-dioxygenase inhibitor
Cas No. 1204669-37-3
别名 4-[[2-[(氨基磺酰基)氨基]乙基]氨基]-N'-(3-溴-4-氟苯基)-N-羟基-1,2,5-恶二唑-3-甲脒
化学名 (E)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-((2-(sulfamoylamino)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide
Canonical SMILES BrC1=CC(/N=C(NO)\C2=NON=C2NCCNS(=O)(N)=O)=CC=C1F
分子式 C11H13BrFN7O4S
分子量 438.23
溶解度 ≥ 19.35mg/mL in DMSO
储存条件 Store at -20℃
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value<100 nM.

IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system.

Reference:
[1]. Andrew P. Combs, et al. 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase. Patent Numeber: EP 2315756 A2
http://www. google.com/patents/EP2315756A2?cl=en

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