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ONO 2506
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ONO 2506图片
CAS NO: 185517-21-9
包装与价格:
包装 价格(元)
10mM (in 1mL DMSO) 电议
10mg 电议
25mg 电议
50mg 电议
100mg 电议

半岛bd体育手机客户端 介绍
Arundic acid (ONO-2506) 是一种星形胶质细胞调节剂,通过抑制 S-100β 来调节星形胶质细胞的活化,从而延缓脑梗死的扩大;合成。
Cas No. 185517-21-9
别名 (R)-(-)-2-丙基辛酸,ONO-2506; (R)-2-Propyloctanoic acid
化学名 (R)-2-propyloctanoic acid
Canonical SMILES OC([C@H](CCC)CCCCCC)=O
分子式 C11H22O2
分子量 186.29
溶解度 <18.63mg/ml in DMSO;<18.63mg/ml in ethanol
储存条件 Store at -20℃
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
半岛bd体育手机客户端 描述

Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].

References:
[1]. Tomoyuki Hasegawa, et al. Process Development of ONO-2506: A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171.
[2]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73.

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