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重组新冠RBD单克隆抗体
重组新冠RBD单克隆抗体图片
型号: MAV101
品牌: 卡梅德生物
参考价格: 3500元/ug
交货期: 2-3天
产地: 天津


包装与价格:
订货号 纯度规格 包装 价格(元)
MAV101 100ug 3500
半岛bd体育手机客户端 介绍
半岛bd体育手机客户端 编号 MAV101
半岛bd体育手机客户端 名称 Recombinant Human anti-COVID-19/SARS-CoV-2 RBD Monoclonal Antibody
抗体亚型 IgG1
规格与价格 100ul/¥3,500; 500ul/¥9,000; 1000ul/¥16,000
克隆号 1G6
半岛bd体育手机客户端 别名 SARS-CoV-2 RBD antibody, 2019-nCoV, Coronavirus
规格 100ul, 500ul
物种 COVID-19
宿主 Human
半岛bd体育手机客户端 应用 ELISA, Colloidal Gold, POCT, Neutralizaiton , Standard Positive Control
内毒素水平 <0.1EU/ug determided by LAL method.
缓冲体系 0.01M PBS, pH 7.4
免疫原 Native virus
半岛bd体育手机客户端 背景 A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans, causing COVID-19. A key to tackling this pandemic is to understand the receptor recognition mechanism of the virus, which regulates its infectivity, pathogenesis and host range. SARS-CoV-2 and SARS-CoV recognize the same receptor—angiotensin-converting enzyme 2 (ACE2)—in humans. Researchers determined the crystal structure of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 (engineered to facilitate crystallization) in complex with ACE2. In comparison with the SARS-CoV RBD, an ACE2-binding ridge in SARS-CoV-2 RBD has a more compact conformation; moreover, several residue changes in the SARS-CoV-2 RBD stabilize two virus-binding hotspots at the RBD–ACE2 interface. These structural features of SARS-CoV-2 RBD increase its ACE2-binding affinity. Additionally, we show that RaTG13, a bat coronavirus that is closely related to SARS-CoV-2, also uses human ACE2 as its receptor.
保存条件 This product can be stored at 2℃-8℃ for one month. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
备注 This product is used for research use only. Not for human or diagnostic use.


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