闈舵爣锛欬p style="text-indent: 2em;">PHOX2A

浜у搧鍒悕锛欬p style="text-indent: 2em;">ARIX锛 CFEOM2锛 FEOM2锛 NCAM2锛 PMX2A锛 PHOX2A锛 paired like homeobox 2A锛 paired like homeobox 2A锛 paired mesoderm homeobox protein 2A锛 ARIX1 homeodomain protein锛 aristaless homeobox homolog锛 aristaless homeobox protein homolog锛 arix homeodomain protein锛 鍏堝ぉ鎬х溂澶栬倢绾ょ淮鍖栫浉鍏宠泲鐧紽EOM2锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">paired like homeobox 2a(PHOX2A) Homo sapiens The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008],