闈舵爣锛欬p style="text-indent: 2em;">Sprn

浜у搧鍒悕锛欬p style="text-indent: 2em;">CG14128锛 Dmel\CG14128锛 sprn锛 Sprn锛 Spermitin锛 Spermitin锛 spermitin锛 CG14128-PB锛 CG14128-PC锛 CG14128-PE锛 CG14128-PF锛 Sprn-PB锛 Sprn-PC锛 Sprn-PE锛 Sprn-PF锛 鏂版湂铔嬬櫧锛 鏂版湂铔嬬櫧锛圕绔級锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">SPRN (shadow of prion protein), also known as SHO or SHADOO, is a 151 amino acid cytoplasmic protein that is mainly expressed in brain. SPRN is considered a prion-like protein that has PrP(C)-like neuroprotective activity and may act as a modulator for the biological actions of normal and abnormal PrP. In humans, mutations in the gene encoding SPRN may be associated with variant and sporadic Creutzfeldt-Jakob disease, a degenerative neurological disorder that is incurable and invariably fatal.