靶标９�p style="text-indent: 2em;">H2-D1

产品别名９�p style="text-indent: 2em;">H-2D� H2-D� H2-K1� H2-D1� histocompatibility 2, D region locus 1� histocompatibility 2, D region locus 1� H-2 class I histocompatibility antigen, D-B alpha chain� H-2D cell surface glycoprotein� H2-DC1-beta transplantation antigen protein� MHC H2-D-q alpha-chain� MHC class I H-2Dp� MHC class I H2 antigen� Q5k protein� I类组织相容性H-2抗原D-Dalpha链；

背景信息９�div style="text-indent: 2em;">The “classical� MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic α chains noncovalently associated with the invariant ?2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8 ⁺T lymphocytes which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8 ⁺T cells during T cell ontogeny.