闈舵爣锛欬p style="text-indent: 2em;">SPIB

浜у搧鍒悕锛欬p style="text-indent: 2em;">SPI-B锛 SPIB锛 Spi-B transcription factor锛 Spi-B transcription factor锛 transcription factor Spi-B锛 Spi-B transcription factor (Spi-1/PU.1 related)锛 杞綍鍥犲瓙SPIB铔嬬櫧锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">Spi-B 灞炰簬 ETS 杞綍鍥犲瓙瀹舵棌锛岄€氳繃鐩存帴缁撳悎 PU 鐩掓縺娲昏浆褰 (1)銆係pi-B 鏍规嵁鍏朵笌 PU.1/Spi-I 鐨勫悓婧愭€ф潵閴村畾 (1)銆傚湪 B 缁嗚優鍜岀被娴嗙粏鑳炴爲绐佺粏鑳 (pDCs) 涓渶娣卞叆鍦扮爺绌 Spi-B 鐨勫姛鑳姐€傜己涔 Spi-B 鐨勫皬榧 B 缁嗚優澧炴畺涓嶄匠锛岃€屼笖鍦ㄥ簲绛 B 缁嗚優鍙椾綋浠嬪鐨勪俊鍙疯浆瀵煎悗浼氭浜 (2)銆傚彟澶栵紝Spi-B ^(-/-)灏忛紶鍦ㄨ儦鑳庝腑蹇冨舰鎴愭椂鏈夌己闄 (2)銆係pi-B 鍦 pDCs 鐨勫彂鑲插拰鍔熻兘涓彂鎸ヤ綔鐢ㄣ€傚畠鐢 pDCs 楂樺害琛ㄨ揪锛岃€岄潪鍗曟牳缁嗚優琛嶇敓鐨 DCs锛岃€屼笖閫犺绁栫粏鑳炰腑 Spi-B 杩囪〃杈句細鎶戝埗鍏朵粬娣嬪反鏍疯氨绯荤粏鑳炵殑鍙戣偛(3)銆 Spi-B ^(-/-)灏忛紶涓殑 pDCs 鍦ㄥ簲绛 TLR7 鍜 TLR9 鍒烘縺鏃朵骇鐢熺殑骞叉壈绱犺緝灏戯紝鑰屼笖鍏 pDC 鐗瑰紓鎬ц〃闈㈡爣璁扮墿鐨勮〃杈炬按骞充篃杈冧綆 (4)銆傛渶鍚庯紝Spi-B 涓哄皬鑲犲井瑜剁粏鑳炲垎鍖栨墍蹇呴渶 (5,6)銆侟/div>

瀹夸富锛歊bt
绫诲瀷锛歅ab
鍚岀鍨婜IgG
搴旂敤锛歐B
绾寲鏂瑰紡锛氫翰鍜岀函鍖朁br/>鍋惰仈鐗╋細Unconjugated
鎬х姸锛氭恫浣
瀛樺偍婧舵恫锛氬弬闃呰鏄庝功
娴撳害锛欱atch dependent (Please refer to the vial label for the specific concentration.)
绋€閲婃瘮渚婜 Optimal dilutions/concentrations should be determined by the end user
鍌ㄥ瓨锛氱粡甯镐娇鐢ㄥ垯4掳C淇濆瓨銆?20掳C淇濆瓨涓嶈秴杩囦袱骞淬€傞伩鍏嶅弽澶嶅喕铻嶃€侟br/>娉ㄦ剰浜嬮」锛氫粎渚涘疄楠屽浣跨敤銆備笉閫傜敤浜庝汉绫绘垨鍔ㄧ墿鐨勪换浣曚复搴婏紝娌荤枟鎴栬瘖鏂敤閫斻€備笉閫傚悎鍔ㄧ墿鎴栦汉绫婚鐢ㄣ€侟/p>