闈舵爣锛欬p style="text-indent: 2em;">RFX1

浜у搧鍒悕锛欬p style="text-indent: 2em;">EFC锛 RFX锛 RFX1锛 regulatory factor X1锛 regulatory factor X1锛 MHC class II regulatory factor RFX1锛 MHC class II regulatory factor RFX锛 enhancer factor C锛 regulatory factor X, 1 (influences HLA class II expression)锛 trans-acting regulatory factor 1锛 transcription factor RFX1锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE).