闈舵爣锛欬p style="text-indent: 2em;">IARS1

浜у搧鍒悕锛欬p style="text-indent: 2em;">GRIDHH锛 IARS锛 ILERS锛 ILRS锛 IRS锛 PRO0785锛 IARS1锛 isoleucyl-tRNA synthetase 1锛 isoleucyl-tRNA synthetase 1锛 isoleucine--tRNA ligase, cytoplasmic锛 isoleucine tRNA ligase 1, cytoplasmic锛 寮備寒姘ㄩ叞tRNA鍚堟垚閰?IARS)锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.