闈舵爣锛欬p style="text-indent: 2em;">CYP2C18

浜у搧鍒悕锛欬p style="text-indent: 2em;">CPCI锛 CYP2C锛 CYP2C17锛 P450-6B/29C锛 P450IIC17锛 CYP2C18锛 cytochrome P450 family 2 subfamily C member 18锛 cytochrome P450 family 2 subfamily C member 18锛 cytochrome P450 2C18锛 (S)-mephenytoin hydroxylase associated cytochrome P450锛 CYPIIC18锛 cytochrome P450, family 2, subfamily C, polypeptide 18锛 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17锛 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18锛 cytochrome P450-6B/29C锛 flavoprotein-linked monooxygenase锛 microsomal monooxygenase锛 unspecific monooxygenase锛 缁嗚優鑹茬礌P450 2C18锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],