闈舵爣锛欬p style="text-indent: 2em;">ATP6V0C

浜у搧鍒悕锛欬p style="text-indent: 2em;">ATP6C锛 ATP6L锛 ATPL锛 VATL锛 VPPC锛 Vma3锛 ATP6V0C锛 ATPase H+ transporting V0 subunit c锛 ATPase H+ transporting V0 subunit c锛 V-type proton ATPase 16 kDa proteolipid subunit c锛 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c锛 H(+)-transporting two-sector ATPase, 16 kDa subunit锛 V-ATPase 16 kDa proteolipid subunit锛 V-ATPase 16 kDa proteolipid subunit c锛 V-type proton ATPase 16 kDa proteolipid subunit锛 vacuolar ATP synthase 16 kDa proteolipid subunit锛 vacuolar H+ ATPase proton channel subunit锛 vacuolar proton pump 16 kDa proteolipid subunit锛 vacuolar proton pump 16 kDa proteolipid subunit c锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L.