闈舵爣锛欬p style="text-indent: 2em;">SHROOM2

浜у搧鍒悕锛欬p style="text-indent: 2em;">APXL锛 HSAPXL锛 SHROOM2锛 shroom family member 2锛 shroom family member 2锛 protein Shroom2锛 APX homolog of Xenopus锛 apical-like protein锛 APXL铔嬬櫧锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene.