应用
6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.

备注
Incompatible materials are oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

基本信息

MDL
MFCD00004988

EINECS
213-804-3

分子式
C₁₃H₉NO

分子量
195.22

熔点
288-294°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in DMSO (5 mg/ml). Insoluble in water.

Beilstein
140641

安全信息

RTECS
SG0370000

TSCA
否