应用
It is reagent used forligand-free palladium-catalyzed Suzuki-Miyaura cross-couplings, ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines, Diels-Alder or C-H activation reactions, regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulations, N-arylation of phenylurea using copper acetylacetonate catalyst, environmentally benign one-pot synthesis through a double arylation process, copper-mediated cyanation, copper-catalyzed arylations regioselective glycosylations. Suzuki couplings followed by arylations, X-ray absorption on rhodium-grafted hydrotalcite catalyst for heterogeneous 1,4-addition reaction of organoboron reagents to electron deficient olefins. It is used in Preparation of combretastatin analogs as potential antitumor agents and human immunodeficiency virus (HIV) protease inhibitors with antiviral activities against drug-resistant viruses

备注
Store in cool dry conditions. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00161360

分子式
C₆H₆BNO₄

分子量
166.93

熔点
ca 285° dec.

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Slightly soluble in water.

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA
否