应用
It is a non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It finds its application as gout suppressant, non-steroidal anti-inflammatory drug and analgesic. It also plays many biological roles. Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.

备注
Store away from oxidizing agents, strong bases and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

基本信息

MDL
MFCD00057095

EINECS
200-186-5

分子式
C₁₉H₁₆ClNO₄

分子量
357.8

熔点
158-161°

灵敏度
Light Sensitive. Ambient temperatures.

形态
Powder

溶解性
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.

Beilstein
497341

Merck
14,4968

GHS危害和防范说明

GHS符号

Hazard Statements
H300-H341
Fatal if swallowed.Suspected of causing genetic defects.

Precautionary Statements
P201-P280-P301+P310a-P308+P313-P405-P501a
Obtain special instructions before use.Wear protective gloves/protective clothing/eye protection/face protection.Wear protective gloves/protective clothing/eye protection/face protection.IF exposed or concerned: Get medical advice/attention.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
II

危险类别
28-68
Very toxic if swallowed.Possible risk of irreversible effects.

安全等级
20-28-36/37-45
When using do not eat or drink.After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer).Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

RTECS
NL3500000

TSCA
是