4-(Hydroxymethyl)tetrahydropyran

应用
Used as a reagent in the identification and optimization of pteridinone Toll-like receptor 7 agonists, which can be used for the oral treatment of viral hepatitis. 4-(Hydroxymethyl)tetrahydropyran is also a starting material for [1-[(Tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone which is a drug that acts as CB2 cannabinoid receptor agonist.

备注
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

基本信息

MDL
MFCD00457804

分子式
C₆H₁₂O₂

分子量
116.16

沸点
111-115°/15mm

闪点
61°(142°F)

折射率
1.4600

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Slightly soluble in water.

Beilstein
103069

GHS危害和防范说明

GHS符号

Hazard Statements
H227-H315-H318-H335
Combustible liquid.Causes skin irritation.Causes serious eye damage.May cause respiratory irritation.

Precautionary Statements
P210e-P261-P280a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
37/38-41
Irritating to respiratory system and skin.Risk of serious damage to eyes.

安全等级
23-26-37/39-60
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable gloves and eye/face protection.This material and its container must be disposed of as hazardous waste

TSCA
否