应用
Glyoxylic acid is a reagent for sulfinylmaleate synthesis. It is one of the chemicals used in the Hopkins Cole reaction. It is involved to check the presence of tryptophan in proteins. It is condensed with urea and 1,2-diaminobenzene to form heterocycles. It also undergoes Friedel-Crafts and cyclocondensation reactions to form bis(pentamethylphenyl) acetic acid and a beta-carboline respectively. It is employed in the synthesis of a sulfinylmaleate, which serves as an efficient dienophile for enantioselective Diels-Alder cycloadditions.

备注
Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible withbases, oxidizing agents and reducing agents.

基本信息

MDL
MFCD00149497

EINECS
206-058-5

分子式
OHCCO₂H?H₂O

分子量
92.06 (74.04anhy)

熔点
48-52°

沸点
100°

闪点
>110°(230°F)

灵敏度
Keep Cold. Hygroscopic. Store under Nitrogen.

形态
Crystalline solid

溶解性
Soluble in water, dimethyl sulfoxide and alcohol. Insoluble in diethyl ether and hydrocarbons.

Beilstein
969535

Merck
14,4511

GHS危害和防范说明

GHS符号

Hazard Statements
H314-H318-H317
Causes severe skin burns and eye damage.Causes serious eye damage.May cause an allergic skin reaction.

Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
II

危险类别
34-43
Causes burns.May cause sensitization by skin contact.

安全等级
20-26-36/37/39-45
When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

RTECS
MD4550000

TSCA
是