应用
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.

备注
Hygroscopic. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from humidity.

基本信息

MDL
MFCD00012871

EINECS
210-787-4

分子式
CH₃CH₂O₂CCH₂NH₂?HCl

分子量
139.58

熔点
144-148°

灵敏度
Hygroscopic. Store under Nitrogen. Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water (>1000 mg/ml at 20°C), ethanol, DMSO, and methanol.

Beilstein
3594034

GHS危害和防范说明

GHS符号

Hazard Statements
H318
Causes serious eye damage.

Precautionary Statements
P280i-P305+P351+P338-P310a
Wear eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
41
Risk of serious damage to eyes.

安全等级
26-39-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear eye/face protection.This material and its container must be disposed of as hazardous waste

RTECS
MC0525000

TSCA
是