应用
Ethyl nitroacetate has been used in the synthesis of γ-oxoacids via Michael addition reaction with α,β-unsaturated ketones, fuctionalization of C4-position on pyrimidine and C6-position on 2?-deoxyguanosine to produce novel nucleosides, facile synthesis of α,α-diisobutylglycine, synthesis of DL-4,4-difluoroglutamic acid. It is also used as an intermediate in the preparation of unsubstituted amino acids.

备注
Store away from bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

基本信息

MDL
MFCD00007403

EINECS
210-944-7

分子式
C₄H₇NO₄

分子量
133.11

沸点
93-95°/10mm

闪点
92°(197°F)

密度
1.202

折射率
1.4240

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Slightly soluble in water. Soluble in chloroform and ethyl acetate.

Beilstein
1210027

GHS危害和防范说明

GHS符号

Hazard Statements
H227-H315-H319
Combustible liquid.Causes skin irritation.Causes serious eye irritation.

Precautionary Statements
P280g-P305+P351+P338
Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
36/38
Irritating to eyes and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
AJ1074000

TSCA
是