应用
Diphenylphosphonic azide acts as a reagent for the synthesis of peptides and phosphoramidates by reacting with amines. It is also used in the preparation of oligosaccharides linked with carbamate and urea bonds utilizing modified Curtis rearrangement. It is involved in pseudohalogen replacement of the azido group by treatment with nucleophilic reagents, such as water, butanol, ammonia, and various amines. Further, it is used as a hydroazidation catalyst for preparation of organoazides.

备注
Store in a cool place. Incompatible with acids and oxidizing agents.

基本信息

MDL
MFCD00001987

EINECS
247-644-0

分子式
C₁₂H₁₀N₃O₃P

分子量
275.20

沸点
161-162°/0.5mm

闪点
>110°(230°F)

密度
1.275

折射率
1.5520

灵敏度
Keep Cold.

形态
Liquid

溶解性
Immiscible with water.

Beilstein
2058967

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H311-H331-H315-H319-H335
Toxic if swallowed.Toxic in contact with skin.Toxic if inhaled.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
II

危险类别
23/24/25-36/37/38
Toxic by inhalation, in contact with skin and if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
4-9-20-23-26-27-36/37/39-45-60
Keep away from living quarters.Keep container in a well-ventilated place.When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Take off immediately all contaminated clothing.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

TSCA
否