应用
2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.

备注
Stable under recommended storage conditions. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00012188

分子式
C₉H₁₃N₃O₃

分子量
211.22

熔点
216-220°

灵敏度
Keep Cold.

形态
Solid

溶解性
Soluble in water (76.4 mg/ml at 25°C), DMSO (42 mg/ml at 25°C), and ethanol (<1 mg/ml at 25°C).

Beilstein
654956

Merck
14,10109

GHS危害和防范说明

GHS符号

Hazard Statements
H351-H361
Suspected of causing cancer.Suspected of damaging fertility or the unborn child.

Precautionary Statements
P201-P280-P202-P308+P313-P405-P501a
Obtain special instructions before use.Wear protective gloves/protective clothing/eye protection/face protection.Do not handle until all safety precautions have been read and understood.IF exposed or concerned: Get medical advice/attention.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
40-62
Limited evidence of a carcinogenic effect.Possible risk of impaired fertility.

安全等级
36/37
Wear suitable protective clothing and gloves.

欧盟危险品标志

RTECS
HA3870000

TSCA
否