应用
trans-Diamminedichloroplatinum(II) acts as a reversible RNA-protein cross-linking agent. It is also used in plating baths. It reacts with DNA after hydrolysis to get both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00011623

EINECS
238-980-9

分子式
Cl₂H₆N₂Pt

分子量
300.06

熔点
340° dec.

灵敏度
Ambient temperatures.

形态
Crystalline

溶解性
Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water.

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H334-H317-H341-H335
Causes skin irritation.Causes serious eye irritation.May cause allergy or asthma symptoms or breathing difficulties if inhaled.May cause an allergic skin reaction.Suspected of causing genetic defects.May cause respiratory irritation.

Precautionary Statements
P261-P262-P280h-P305+P351+P338-P308+P313
Avoid breathing dust/fume/gas/mist/vapours/spray.Do not get in eyes, on skin, or on clothing.Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or concerned: Get medical advice/attention.

安全信息

危险等级
6.1

包装组
II

危险类别
36/37/38-42/43-68
Irritating to eyes, respiratory system and skin.May cause sensitization by inhalation and skin contact.Possible risk of irreversible effects.

安全等级
22-24-26-36/37-45
Do not breathe dust.Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

RTECS
TP2455000

TSCA
否