应用
One-step synthesis of carbametacyclophane 3 from 1,9-decadiyne and diethyl acetylenedicarboxylate is described. The use of 1,9-decadiyne as a nucleophile led only to the monoalkynylation product, a selectivity that would be difficult to achieve with a catalytic in situ metalation process. 1,9-decadiyne reacts with iodobenzene (excess) to afford the bis-Sonogashira coupling product in excellent yield. 1,9-Decadiyne was dihydrated and gave 2,9-decanedione in 92% yield.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

基本信息

MDL
MFCD00014926

EINECS
217-012-9

分子式
HC≡C(CH₂)₆C≡CH

分子量
134.22

沸点
80-81°/10mm

闪点
60°(140°F)

密度
0.822

折射率
1.4510

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Insoluble in water.

Beilstein
1734594

GHS危害和防范说明

GHS符号

Hazard Statements
H226
Flammable liquid and vapour.

Precautionary Statements
P210-P280a-P240-P241-P303+P361+P353-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Wear protective gloves and eye/face protection.Ground/bond container and receiving equipment.Use explosion-proof electrical/ventilating/lighting/ equipment.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
3

包装组
III

TSCA
是