应用
3-Chloro-5-fluorophenol is used as an intermediate in organic synthesis. It plays an important role in the preparation of substituted amides as antagonists and/or inverse agonists of cannabinoid-1 receptor, substituted N-(arylmethyl)aryloxy arylcarboxamide and heteroarylcarboxamide antagonists for the PGE2 receptor EP4 for the treatment of pain, inflammation, osteoarthritis, and rheumatoid arthritis.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00042212

EINECS
None

分子式
C₆H₄ClFO

分子量
146.55

折射率
1.537

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Immiscible with water.

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H312-H314-H318-H401-H411
Harmful if swallowed.Harmful in contact with skin.Causes severe skin burns and eye damage.Causes serious eye damage.Toxic to aquatic life.Toxic to aquatic life with long lasting effects.

Precautionary Statements
P273-P280-P303+P361+P353-P305+P351+P338-P310
Avoid release to the environment.Wear protective gloves/protective clothing/eye protection/face protection.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Immediately call a POISON CENTER or doctor/physician.

安全信息

危险等级
8

包装组
III

危险类别
21/22-34-51/53
Harmful in contact with skin and if swallowed.Causes burns.Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

安全等级
26-36/37/39-45-61
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).Avoid release to the environment. Refer to special instructions/safety data sheets.

欧盟危险品标志

TSCA
否