应用
tert-Butyl diethylphosphonoacetate is used as a reactant for preparation of hydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents, synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3) and bicyclic triaminophosphine-promoted stereoselective synthesis of a,??-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00075414

EINECS
000-000-0

分子式
C₁₀H₂₁O₅P

分子量
252.25

沸点
100-103°/1.5mm

闪点
>110°(230°F)

密度
1.074

折射率
1.4310

灵敏度
Ambient temperatures.

溶解性
Not miscible or difficult to mix in water.

Beilstein
2050126

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319
Causes skin irritation.Causes serious eye irritation.

Precautionary Statements
P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313
Wear protective gloves and eye/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment (see label).If skin irritation occurs: Get medical advice/attention.If eye irritation persists: Get medical advice/attention.

安全信息

危险类别
36/38
Irritating to eyes and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA
否